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Symbol
Name
ID
Foxc1
forkhead box C1
MGI:1347466
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Cerebellar vermis hypoplasia
Disease(s) Associated with FOXC1
Axenfeld-Rieger syndrome type 3

Mouse Phenotypes
nervous system phenotype
intracranial hemorrhage
abnormal neuron differentiation
abnormal radial glial cell morphology
radial glial endfoot detachment
abnormal neuron proliferation
abnormal roof plate morphology
abnormal pituitary diverticulum morphology
abnormal pituitary gland development
abnormal brain development
abnormal forebrain development
abnormal cortical marginal zone morphology
abnormal cerebellum development
hydrocephaly
non-obstructive hydrocephaly
abnormal brain ventricular system morphology
abnormal fourth ventricle morphology
abnormal lateral ventricle morphology
dilated lateral ventricle
abnormal choroid plexus morphology
abnormal third ventricle morphology
abnormal cerebral aqueduct morphology
absent corpus callosum
abnormal forebrain morphology
abnormal striatum morphology
abnormal hippocampus morphology
abnormal cerebral cortex morphology
abnormal neocortex morphology
abnormal stratification in cerebral cortex
abnormal meninges morphology
abnormal brain meninges morphology
abnormal nervous system development
ectopic neuron
abnormal trigeminal ganglion morphology
abnormal spinal cord morphology
Availability Mouse Genotype
Foxc1ch/Foxc1ch
Foxc1hith/Foxc1hith
Foxc1hith/Foxc1hith
Tg(Rr291-lacZ)#Mekk/0
Foxc1tm1.1Tsku/Foxc1tm1.1Tsku
Foxc1tm1Blh/Foxc1tm1Blh
Foxc1ch/Foxc1+ *
Foxc1hith/Foxc1tm1Blh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory